Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
This Human ITPKB recombinant protein was produced in E.coli, where the gene sequence encoding Human ITPKB (442-946aa) was expressed with the N-terminal 6xHis-SUMO tag. The purity of this ITPKB protein was greater than 90% by SDS-PAGE.ITPKB is an enzyme, and its primary function is to phosphorylate inositol trisphosphate (IP3), converting it into inositol tetrakisphosphate (IP4). IP3 and IP4 are important cellular signaling molecules that play a crucial role in the regulation of intracellular calcium ions (Ca2+). In particular, IP3 is considered a trigger for the release of intracellular Ca2+. ITPKB is involved in intracellular calcium ion signaling pathways by regulating the concentrations of IP3 and IP4. These signaling pathways are essential for various cellular processes, including cell proliferation, differentiation, migration, and apoptosis. ITPKB is also believed to be associated with cell cycle regulation. Research has shown that the activity of ITPKB can be influenced by cell cycle regulatory proteins, thereby affecting cell division and proliferation.
This Human ITPKB recombinant protein was produced in E.coli, where the gene sequence encoding Human ITPKB (442-946aa) was expressed with the N-terminal 6xHis-SUMO tag. The purity of this ITPKB protein was greater than 90% by SDS-PAGE.ITPKB is an enzyme, and its primary function is to phosphorylate inositol trisphosphate (IP3), converting it into inositol tetrakisphosphate (IP4). IP3 and IP4 are important cellular signaling molecules that play a crucial role in the regulation of intracellular calcium ions (Ca2+). In particular, IP3 is considered a trigger for the release of intracellular Ca2+. ITPKB is involved in intracellular calcium ion signaling pathways by regulating the concentrations of IP3 and IP4. These signaling pathways are essential for various cellular processes, including cell proliferation, differentiation, migration, and apoptosis. ITPKB is also believed to be associated with cell cycle regulation. Research has shown that the activity of ITPKB can be influenced by cell cycle regulatory proteins, thereby affecting cell division and proliferation.
| Cat.No | ACP03585 | Target Name | ITPKB |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 442-946aa | Mol Weight | 72.5kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P27987 |
|---|
Uniprot Id
P27987
Target Species
Human
Target Name
ITPKB
Target Full Name
Inositol-trisphosphate 3-kinase B
Target Research Area
Signal Transduction
Target Synonyms
1D myo inositol trisphosphate 3 kinase B; 4; 5-trisphosphate 3-kinase B; Inositol 1 4 5 trisphosphate 3 kinase B; Inositol 1; Inositol trisphosphate 3 kinase B; Inositol-trisphosphate 3-kinase B; InsP 3-kinase B; IP3 3 kinase; IP3 3 kinase B; IP3 3-kinase B; IP3K; IP3K B; IP3KB; IP3KB_HUMAN; Itpkb
Target Background
The protein encoded by this protein regulates inositol phosphate metabolism by phosphorylation of second messenger inositol 1, 4, 5-trisphosphate to Ins(1, 3, 4, 5)P4. The activity of this encoded protein is responsible for regulating the levels of a large number of inositol polyphosphates that are important in cellular signaling. Both calcium/calmodulin and protein phosphorylation mechanisms control its activity.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
