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| Cat.No | ACP24153 | Target Name | MX2 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-715 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P20592 |
|---|
Uniprot Id
P20592
Target Species
Human
Target Name
MX2
Target Full Name
Interferon-induced GTP-binding protein Mx2
Target Function
Interferon-induced dynamin-like GTPase with potent antiviral activity against human immunodeficiency virus type 1 (HIV-1). Acts by targeting the viral capsid and affects the nuclear uptake and/or stability of the HIV-1 replication complex and the subsequent chromosomal integration of the proviral DNA. Exhibits antiviral activity also against simian immunodeficiency virus (SIV-mnd). May play a role in regulating nucleocytoplasmic transport and cell-cycle progression.
Target Subcellular Location
Cytoplasm. Nucleus. Nucleus, nuclear pore complex. Note=Localization to nuclear pores requires GTP-binding.
Target Protein Families
TRAFAC class dynamin-like GTPase superfamily, Dynamin/Fzo/YdjA family
Target Synonyms
Interferon induced GTP binding protein Mx2; Interferon regulated resistance GTP binding protein MXB; Interferon-induced GTP-binding protein Mx2; Interferon-regulated resistance GTP-binding protein MxB; MX 2; MX dynamin like GTPase 2; Mx2; MX2_HUMAN; MXB; Myxovirus (influenza virus) resistance 2; Myxovirus resistance 2; Myxovirus resistance protein 2; p78 related protein; p78-related protein; Second interferon induced protein p78
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