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Recombinant Human Intracellular hyaluronan-binding protein 4 (HABP4)

ACP17360

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP17360 Target NameHABP4
Target SynonymsHABP4; Intracellular hyaluronan-binding protein 4; IHABP-4; IHABP4; Hyaluronan-binding protein 4; Ki-1/57 intracellular antigenFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-413
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ5JVS0
Background Information
  • Uniprot Id

    Q5JVS0

  • Target Species

    Human

  • Target Name

    HABP4

  • Target Full Name

    Intracellular hyaluronan-binding protein 4

  • Target Function

    RNA-binding protein that plays a role in the regulation of transcription, pre-mRNA splicing and mRNA translation. Negatively regulates DNA-binding activity of the transcription factor MEF2C in myocardial cells in response to mechanical stress. Plays a role in pre-mRNA splicing regulation. Binds (via C-terminus) to poly(U) RNA. Involved in mRNA translation regulation, probably at the initiation step. Seems to play a role in PML-nuclear bodies formation.

  • Target Subcellular Location

    Nucleus. Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, sarcoplasm. Nucleus, nuclear body. Nucleus, nucleolus. Nucleus speckle. Nucleus, Cajal body. Nucleus, gem.

  • Target Tissue Specificity

    Highly expressed in brain, heart, and kidney, and moderately expressed in skeletal muscle. Also expressed in a variety of tumor cell lines and in activated but not resting leukocytes.

  • Target Synonyms

    HABP4; Intracellular hyaluronan-binding protein 4; IHABP-4; IHABP4; Hyaluronan-binding protein 4; Ki-1/57 intracellular antigen

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