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| Cat.No | ACP11855 | Target Name | IQCG |
|---|---|---|---|
| Target Synonyms | IQCG; DRC9Dynein regulatory complex protein 9; IQ domain-containing protein G | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-443 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H095 |
|---|
Uniprot Id
Q9H095
Target Species
Human
Target Name
IQCG
Target Full Name
Dynein regulatory complex protein 9
Target Function
Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes. Binds calmodulin when cellular Ca(2+) levels are low and thereby contributes to the regulation of calcium and calmodulin-dependent protein kinase IV (CAMK4) activity; contributes to the regulation of CAMK4 signaling cascades. Required for normal axoneme assembly in sperm flagella, normal sperm tail formation and for male fertility.
Target Subcellular Location
Cytoplasm. Cell projection, cilium, flagellum. Cell projection, cilium. Cytoplasm, cytoskeleton. Cytoplasm, cytoskeleton, flagellum axoneme.
Target Protein Families
DRC9 family
Target Synonyms
IQCG; DRC9Dynein regulatory complex protein 9; IQ domain-containing protein G
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