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| Cat.No | ACP20833 | Target Name | KLHL2 |
|---|---|---|---|
| Target Synonyms | ABP KELCH ; Actin binding protein Mayven ; Actin-binding protein Mayven; kelch; kelch like 2; Kelch like 2, Mayven; Kelch like family member 2; Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN ; OTTHUMP00000219997; OTTHUMP00000219998 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-593 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O95198 |
|---|
Uniprot Id
O95198
Target Species
Human
Target Name
KLHL2
Target Full Name
Kelch-like protein 2
Target Function
Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, such as NPTXR, leading most often to their proteasomal degradation. Responsible for degradative ubiquitination of the WNK kinases WNK1, WNK3 and WNK4. Plays a role in the reorganization of the actin cytoskeleton. Promotes growth of cell projections in oligodendrocyte precursors.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cell projection, ruffle. Cell projection. Cell projection, lamellipodium. Cytoplasm, cytosol.
Target Tissue Specificity
Ubiquitous. Detected throughout the brain.
Target Synonyms
ABP KELCH ; Actin binding protein Mayven ; Actin-binding protein Mayven; kelch; kelch like 2; Kelch like 2, Mayven; Kelch like family member 2; Kelch like protein 2; Kelch-like protein 2; KLHL2; KLHL2_HUMAN; MAV; MAYVEN ; OTTHUMP00000219997; OTTHUMP00000219998
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