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| Cat.No | ACP16879 | Target Name | LCE3B |
|---|---|---|---|
| Target Synonyms | LCE3B; LEP14Late cornified envelope protein 3B; Late envelope protein 14 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-95 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5TA77 |
|---|
Uniprot Id
Q5TA77
Target Species
Human
Target Name
LCE3B
Target Full Name
Late cornified envelope protein 3B
Target Function
A structural component of the cornified envelope of the stratum corneum involved in innate cutaneous host defense (Probable). Possesses defensin-like antimicrobial activity against a broad spectrum of Gram-positive and Gram-negative bacteria, both aerobic and anaerobic species. Upon inflammation, may regulate skin barrier repair by shaping cutaneous microbiota composition and immune response to bacterial antigens.
Target Protein Families
LCE family
Target Tissue Specificity
Skin-specific. Expression was readily detected in adult trunk skin, adult arm skin, fetal skin, penal skin, vulva, esophagus and tongue. Not expressed in the cervix, rectum, lung, colon, or placenta.
Target Synonyms
LCE3B; LEP14Late cornified envelope protein 3B; Late envelope protein 14
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