Home Products Proteins Recombinant Proteins Recombinant Human Latent-transforming growth factor beta-binding protein 3 (LTBP3), Truncated

Recombinant Human Latent-transforming growth factor beta-binding protein 3 (LTBP3), Truncated

ACP10272

Number

Order Exclusive Products Now

Request a Quote

High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP10272	Target Name	LTBP3
Target Synonyms	LTBP3; Latent-transforming growth factor beta-binding protein 3; LTBP-3	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9NS15

Background Information

Uniprot Id

Q9NS15
Target Species

Human
Target Name

LTBP3
Target Full Name

Latent-transforming growth factor beta-binding protein 3
Target Function

Key regulator of transforming growth factor beta (TGFB1, TGFB2 and TGFB3) that controls TGF-beta activation by maintaining it in a latent state during storage in extracellular space. Associates specifically via disulfide bonds with the Latency-associated peptide (LAP), which is the regulatory chain of TGF-beta, and regulates integrin-dependent activation of TGF-beta.
Target Involvement

Dental anomalies and short stature (DASS)
Target Subcellular Location

Secreted. Secreted, extracellular space, extracellular matrix.
Target Protein Families

LTBP family
Target Tissue Specificity

Isoform 2: Expressed prominently in heart, skeletal muscle, prostate, testis, small intestine and ovary. Isoform 1: Strongly expressed in pancreas and liver.
Target Synonyms

LTBP3; Latent-transforming growth factor beta-binding protein 3; LTBP-3
Target Background

The protein encoded by this gene forms a complex with transforming growth factor beta (TGF-beta) proteins and may be involved in their subcellular localization. Activation of this complex requires removal of the encoded binding protein. This protein also may play a structural role in the extracellular matrix. Three transcript variants encoding different isoforms have been found for this gene.

Inquire Recombinant Human Latent-transforming growth factor beta-binding protein 3 (LTBP3), Truncated Now

Full Name *

Business Email Address *

Phone

Products/Services

Catalog Number

Quantity (μg, mg, g, μl, ml, L, kit)

Address

Project Description

AbTriva respects your privacy and protects your personal data in accordance with AbTriva. For more information, please see our data protection statement. *

Submit

Recombinant Human Latent-transforming growth factor beta-binding protein 3 (LTBP3), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Latent-transforming growth factor beta-binding protein 3 (LTBP3), Truncated Now

Related Products