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| Cat.No | ACP13769 | Target Name | LURAP1 |
|---|---|---|---|
| Target Synonyms | LURAP1; C1orf190; LRAP35A; LRP35A; Leucine rich adaptor protein 1; Leucine repeat adapter protein 35A | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-239 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96LR2 |
|---|
Uniprot Id
Q96LR2
Target Species
Human
Target Name
LURAP1
Target Full Name
Leucine rich adaptor protein 1
Target Function
Acts as an activator of the canonical NF-kappa-B pathway and drive the production of proinflammatory cytokines. Promotes the antigen (Ag)-presenting and priming function of dendritic cells via the canonical NF-kappa-B pathway. In concert with MYO18A and CDC42BPA/CDC42BPB, is involved in modulating lamellar actomyosin retrograde flow that is crucial to cell protrusion and migration. Activates CDC42BPA/CDC42BPB and targets it to actomyosin through its interaction with MYO18A, leading to MYL9/MLC2 phosphorylation and MYH9/MYH10-dependent actomyosin assembly in the lamella.
Target Subcellular Location
Cytoplasm.
Target Synonyms
LURAP1; C1orf190; LRAP35A; LRP35A; Leucine rich adaptor protein 1; Leucine repeat adapter protein 35A
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