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| Cat.No | ACP17075 | Target Name | CARMIL1 |
|---|---|---|---|
| Target Synonyms | Acan 125; Capping protein; Arp2/3; and myosin I linker; CARMIL homolog; leucine rich repeat containing 16; Leucine-rich repeat-containing protein 16A; LR16A_HUMAN; Lrrc16 protein; LRRC16A; p116 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q5VZK9 |
|---|
Uniprot Id
Q5VZK9
Target Species
Human
Target Name
CARMIL1
Target Full Name
F-actin-uncapping protein LRRC16A
Target Function
Cell membrane-cytoskeleton-associated protein that plays a role in the regulation of actin polymerization at the barbed end of actin filaments. Prevents F-actin heterodimeric capping protein (CP) activity at the leading edges of migrating cells, and hence generates uncapped barbed ends and enhances actin polymerization, however, seems unable to nucleate filaments. Plays a role in lamellipodial protrusion formations and cell migration.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton. Cell membrane. Cell projection, lamellipodium.
Target Protein Families
CARMIL family
Target Tissue Specificity
Expressed in lung, placenta, small intestine, liver, thymus, colon, skeletal muscle, heart and brain. Higher expression in kidney.
Target Synonyms
Acan 125; Capping protein; Arp2/3; and myosin I linker; CARMIL homolog; leucine rich repeat containing 16; Leucine-rich repeat-containing protein 16A; LR16A_HUMAN; Lrrc16 protein; LRRC16A; p116
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