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Recombinant Human Leucine-rich repeat transmembrane protein FLRT2 (FLRT2), Truncated

ACP06321

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP06321 Target NameFLRT2
Target SynonymsFLRT2; KIAA0405; UNQ232/PRO265; Leucine-rich repeat transmembrane protein FLRT2; Fibronectin-like domain-containing leucine-rich transmembrane protein 2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO43155
Background Information
  • Uniprot Id

    O43155

  • Target Species

    Human

  • Target Name

    FLRT2

  • Target Full Name

    Leucine-rich repeat transmembrane protein FLRT2

  • Target Function

    Functions in cell-cell adhesion, cell migration and axon guidance. Mediates cell-cell adhesion via its interactions with ADGRL3 and probably also other latrophilins that are expressed at the surface of adjacent cells. May play a role in the migration of cortical neurons during brain development via its interaction with UNC5D. Mediates axon growth cone collapse and plays a repulsive role in neuron guidance via its interaction with UNC5D, and possibly also other UNC-5 family members. Plays a role in fibroblast growth factor-mediated signaling cascades. Required for normal organization of the cardiac basement membrane during embryogenesis, and for normal embryonic epicardium and heart morphogenesis

  • Target Subcellular Location

    Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane. Cell junction, focal adhesion. Secreted, extracellular space, extracellular matrix. Microsome membrane. Secreted. Cell junction, synapse, synaptosome.

  • Target Tissue Specificity

    Expressed in pancreas, skeletal muscle, brain, and heart.

  • Target Synonyms

    FLRT2; KIAA0405; UNQ232/PRO265; Leucine-rich repeat transmembrane protein FLRT2; Fibronectin-like domain-containing leucine-rich transmembrane protein 2

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