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| Cat.No | ACP02489 | Target Name | LST1 |
|---|---|---|---|
| Target Synonyms | LST1; B144; Leukocyte-specific transcript 1 protein; Protein B144 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 1-66aa |
| Mol Weight | 11.5 kDa | Protein Length | Full Length of Isoform 10 |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O00453 |
|---|
Uniprot Id
O00453
Target Species
Human
Target Name
LST1
Target Full Name
Leukocyte-specific transcript 1 protein
Target Function
Possible role in modulating immune responses. Induces morphological changes including production of filopodia and microspikes when overexpressed in a variety of cell types and may be involved in dendritic cell maturation. Isoform 1 and isoform 2 have an inhibitory effect on lymphocyte proliferation.
Target Subcellular Location
Membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein. Endomembrane system; Single-pass membrane protein. Note=Also detected in a perinuclear region corresponding to the localization of the Golgi apparatus and throughout the cytoplasm.
Target Protein Families
LST1 family
Target Tissue Specificity
Expressed in lung, tonsil, thymus, placenta, kidney, fetal spleen, fetal liver and brain.
Target Research Area
Cancer
Target Synonyms
LST1; B144; Leukocyte-specific transcript 1 protein; Protein B144
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