Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
| Cat.No | ACP09089 | Target Name | LAX1 |
|---|---|---|---|
| Target Synonyms | LAX1; LAX; Lymphocyte transmembrane adapter 1; Linker for activation of X cells; Membrane-associated adapter protein LAX | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IWV1 |
|---|
Uniprot Id
Q8IWV1
Target Species
Human
Target Name
LAX1
Target Full Name
Lymphocyte transmembrane adapter 1
Target Function
Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and BCR (B-cell antigen receptor)-mediated signaling in B-cells.
Target Subcellular Location
Cell membrane; Single-pass type III membrane protein.
Target Tissue Specificity
Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.
Target Synonyms
LAX1; LAX; Lymphocyte transmembrane adapter 1; Linker for activation of X cells; Membrane-associated adapter protein LAX
Target Background
Enables SH2 domain binding activity and protein kinase binding activity. Involved in several processes, including B cell activation; negative regulation of MAP kinase activity; and negative regulation of T cell activation. Located in Golgi apparatus; cytosol; and plasma membrane. Is integral component of membrane.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
