Home Products Recombinant Human Lysine-specific demethylase 5D (KDM5D), Truncated

Recombinant Human Lysine-specific demethylase 5D (KDM5D), Truncated

ACP12170

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications

Cat.No	ACP12170	Target Name	KDM5D
Form	Lyophilized powder	Expression System	Custom Production. Please inquire and provide the desire expression system.
Protein Length	Partial	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9BY66

Background Information

Uniprot Id

Q9BY66
Target Species

Human
Target Name

KDM5D
Target Full Name

Lysine-specific demethylase 5D
Target Function

Histone demethylase that specifically demethylates 'Lys-4' of histone H3, thereby playing a central role in histone code. Does not demethylate histone H3 'Lys-9', H3 'Lys-27', H3 'Lys-36', H3 'Lys-79' or H4 'Lys-20'. Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-4'. May play a role in spermatogenesis. Involved in transcriptional repression of diverse metastasis-associated genes; in this function seems to cooperate with ZMYND8. Suppresses prostate cancer cell invasion. Regulates androgen receptor (AR) transcriptional activity by demethylating H3K4me3 active transcription marks
Target Subcellular Location

Nucleus.
Target Protein Families

JARID1 histone demethylase family
Target Tissue Specificity

Expression is highly down-regulated in metastatic prostate tumors.
Target Synonyms

H-Y; Histocompatibility Y antigen; Histone demethylase JARID1D; HY; HYA; JAD1D; Jumonji AT rich interactive domain 1D (RBP2 like); Jumonji/ARID domain-containing protein 1D; KDM5D; KDM5D_HUMAN; KIAA0234; Lysine (K) specific demethylase 5D; Lysine demethylase 5D; Lysine-specific demethylase 5D; Protein SmcY; Selected mouse cDNA on Y human homolog of; SMC homolog Y chromosome; Smcy homolog Y linked

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Recombinant Human Lysine-specific demethylase 5D (KDM5D), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Lysine-specific demethylase 5D (KDM5D), Truncated Now

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