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| Cat.No | ACP15060 | Target Name | MGA |
|---|---|---|---|
| Target Synonyms | MGA; KIAA0518; MAD5MAX gene-associated protein; MAX dimerization protein 5 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IWI9 |
|---|
Uniprot Id
Q8IWI9
Target Species
Human
Target Name
MGA
Target Full Name
MAX gene-associated protein
Target Function
Functions as a dual-specificity transcription factor, regulating the expression of both MAX-network and T-box family target genes. Functions as a repressor or an activator. Binds to 5'-AATTTCACACCTAGGTGTGAAATT-3' core sequence and seems to regulate MYC-MAX target genes. Suppresses transcriptional activation by MYC and inhibits MYC-dependent cell transformation. Function activated by heterodimerization with MAX. This heterodimerization serves the dual function of both generating an E-box-binding heterodimer and simultaneously blocking interaction of a corepressor.
Target Subcellular Location
Nucleus.
Target Synonyms
MGA; KIAA0518; MAD5MAX gene-associated protein; MAX dimerization protein 5
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