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Recombinant Human Melanocortin-2 receptor accessory protein (MRAP), Truncated

ACP05850

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP05850 Target NameMRAP
Target SynonymsB27; C21orf61; FALP; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; FGD2; GCCD2; Melanocortin-2 receptor accessory protein; Mrap; MRAP_HUMANFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Protein LengthPartial
Purity>85% (SDS-PAGE)Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ8TCY5
Background Information
  • Uniprot Id

    Q8TCY5

  • Target Species

    Human

  • Target Name

    MRAP

  • Target Full Name

    Melanocortin-2 receptor accessory protein

  • Target Function

    Modulator of melanocortin receptors (MC1R, MC2R, MC3R, MC4R and MC5R). Acts by increasing ligand-sensitivity of melanocortin receptors and enhancing generation of cAMP by the receptors. Required both for MC2R trafficking to the cell surface of adrenal cells and for signaling in response to corticotropin (ACTH). May be involved in the intracellular trafficking pathways in adipocyte cells.

  • Target Involvement

    Glucocorticoid deficiency 2 (GCCD2)

  • Target Subcellular Location

    Cell membrane; Single-pass membrane protein. Endoplasmic reticulum membrane; Single-pass membrane protein.

  • Target Protein Families

    MRAP family

  • Target Tissue Specificity

    Expressed in adrenal cortex, testis, breast, thyroid, lymph node, ovary and fat. Expressed in adipose tissues.

  • Target Synonyms

    B27; C21orf61; FALP; Fat cell-specific low molecular weight protein; Fat tissue-specific low MW protein; FGD2; GCCD2; Melanocortin-2 receptor accessory protein; Mrap; MRAP_HUMAN

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