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| Cat.No | ACP18041 | Target Name | MTF1 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 2-753 | Protein Length | Full Length of Mature Protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14872 |
|---|
Uniprot Id
Q14872
Target Species
Human
Target Name
MTF1
Target Full Name
Metal regulatory transcription factor 1
Target Function
Zinc-dependent transcriptional regulator of cellular adaption to conditions of exposure to heavy metals. Binds to metal responsive elements (MRE) in promoters and activates the transcription of metallothionein genes like metallothionein-2/MT2A. Also regulates the expression of metalloproteases in response to intracellular zinc and functions as a catabolic regulator of cartilages.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Synonyms
Metal regulatory transcription factor 1; Metal response element binding transcription factor 1; Metal responsive transcription factor 1; MRE binding transcription factor ; MRE-binding transcription factor 1; MRE-binding transcription factor; MTF 1; MTF1; MTF1_HUMAN; Transcription factor MTF-1; Transcription factor MTF1; Zinc regulatory factor; ZRF
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