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| Cat.No | ACP08153 | Target Name | CNNM4 |
|---|---|---|---|
| Target Synonyms | CNNM4; ACDP4; KIAA1592; Metal transporter CNNM4; Ancient conserved domain-containing protein 4; Cyclin-M4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6P4Q7 |
|---|
Uniprot Id
Q6P4Q7
Target Species
Human
Target Name
CNNM4
Target Full Name
Metal transporter CNNM4
Target Function
Probable metal transporter. The interaction with the metal ion chaperone COX11 suggests that it may play a role in sensory neuron functions. May play a role in biomineralization and retinal function.
Target Involvement
Jalili syndrome (JALIS)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
ACDP family
Target Tissue Specificity
Widely expressed. Highly expressed in heart.
Target Synonyms
CNNM4; ACDP4; KIAA1592; Metal transporter CNNM4; Ancient conserved domain-containing protein 4; Cyclin-M4
Target Background
This gene encodes a member of the ancient conserved domain containing protein family. Members of this protein family contain a cyclin box motif and have structural similarity to the cyclins. The encoded protein may play a role in metal ion transport. Mutations in this gene are associated with Jalili syndrome which consists of cone-rod dystrophy and amelogenesis imperfecta.
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