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| Cat.No | ACP14939 | Target Name | MICALL2 |
|---|---|---|---|
| Target Synonyms | MICALL2; JRAB; MICAL-like protein 2; Junctional Rab13-binding protein; Molecule interacting with CasL-like 2; MICAL-L2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IY33 |
|---|
Uniprot Id
Q8IY33
Target Species
Human
Target Name
MICALL2
Target Full Name
MICAL-like protein 2
Target Function
Effector of small Rab GTPases which is involved in junctional complexes assembly through the regulation of cell adhesion molecules transport to the plasma membrane and actin cytoskeleton reorganization. Regulates the endocytic recycling of occludins, claudins and E-cadherin to the plasma membrane and may thereby regulate the establishment of tight junctions and adherens junctions. In parallel, may regulate actin cytoskeleton reorganization directly through interaction with F-actin or indirectly through actinins and filamins. Most probably involved in the processes of epithelial cell differentiation, cell spreading and neurite outgrowth
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Cell junction, tight junction. Recycling endosome. Cell projection. Cytoplasm, cytoskeleton. Cytoplasm, cytosol.
Target Synonyms
MICALL2; JRAB; MICAL-like protein 2; Junctional Rab13-binding protein; Molecule interacting with CasL-like 2; MICAL-L2
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