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| Cat.No | ACP19241 | Target Name | MAP6 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Protein Length | Partial | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96JE9 |
|---|
Uniprot Id
Q96JE9
Target Species
Human
Target Name
MAP6
Target Full Name
Microtubule-associated protein 6
Target Function
Involved in microtubule stabilization in many cell types, including neuronal cells. Specifically has microtubule cold stabilizing activity. Involved in dendrite morphogenesis and maintenance by regulating lysosomal trafficking via its interaction with TMEM106B. Regulates KIF5A-mediated axonal cargo transport. Regulates axonal growth during neuron polarization.
Target Subcellular Location
Cytoplasm, cytoskeleton. Golgi apparatus. Cell projection, axon. Cell projection, dendrite. Cytoplasmic vesicle, secretory vesicle membrane; Lipid-anchor; Cytoplasmic side.
Target Protein Families
STOP family
Target Tissue Specificity
Expressed in brain (at protein level). Expressed in spinal cord. Isoform 2 expression is up-regulated in the prefrontal cortex (Brodmann's area 46) of patients with schizophrenia (postmortem brain study).
Target Synonyms
FLJ41346; KIAA1878; MAP 6; MAP-6; MAP6; MAP6_HUMAN; Microtubule associated protein 6; Microtubule-associated protein 6; MTAP6; N STOP; Stable tubule only polypeptide; Stable tubule-only polypeptide; STOP
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