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| Cat.No | ACP07270 | Target Name | SLC25A22 |
|---|---|---|---|
| Target Synonyms | SLC25A22; GC1; Mitochondrial glutamate carrier 1; GC-1; Glutamate/H(+ symporter 1; Solute carrier family 25 member 22 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9H936 |
|---|
Uniprot Id
Q9H936
Target Species
Human
Target Name
SLC25A22
Target Full Name
Mitochondrial glutamate carrier 1
Target Function
Involved in the transport of glutamate across the inner mitochondrial membrane. Glutamate is cotransported with H(+).
Target Involvement
Epileptic encephalopathy, early infantile, 3 (EIEE3)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Mitochondrial carrier (TC 2.A.29) family
Target Tissue Specificity
Highly expressed in most tissues.
Target Synonyms
SLC25A22; GC1; Mitochondrial glutamate carrier 1; GC-1; Glutamate/H(+ symporter 1; Solute carrier family 25 member 22
Target Background
This gene encodes a mitochondrial glutamate carrier. Mutations in this gene are associated with early infantile epileptic encephalopathy. Multiple alternatively spliced variants, encoding the same protein, have been identified.
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