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This Recombinant Human MORC3 protein is expertly crafted to facilitate your research needs. This high-quality, partial protein (1-290aa) is expressed in E. coli and comes with an N-terminal 6xHis-SUMO-tag, ensuring easy purification and detection. With a purity of greater than 90% as confirmed by SDS-PAGE, our MORC3 protein offers reliable and consistent results. Investigate the complex world of MORC family CW-type zinc finger proteins and their functions with our advanced recombinant protein. Available in both liquid and lyophilized powder forms, our Recombinant Human MORC3 protein is a versatile and valuable addition to your research toolkit.
This Recombinant Human MORC3 protein is expertly crafted to facilitate your research needs. This high-quality, partial protein (1-290aa) is expressed in E. coli and comes with an N-terminal 6xHis-SUMO-tag, ensuring easy purification and detection. With a purity of greater than 90% as confirmed by SDS-PAGE, our MORC3 protein offers reliable and consistent results.
Investigate the complex world of MORC family CW-type zinc finger proteins and their functions with our advanced recombinant protein. Available in both liquid and lyophilized powder forms, our Recombinant Human MORC3 protein is a versatile and valuable addition to your research toolkit.
| Cat.No | ACP02378 | Target Name | MORC3 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 1-290aa | Mol Weight | 48.7kDa |
| Protein Length | Partial | Purity | Greater than 90% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q14149 |
|---|
Uniprot Id
Q14149
Target Species
Human
Target Name
MORC3
Target Full Name
MORC family CW-type zinc finger protein 3
Target Function
Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism. Sumoylated MORC3-NBs can also associate with PML-NBs. Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity. Binds RNA in vitro. May be required for influenza A transcription during viral infection. Histone methylation reader which binds to non-methylated (H3K4me0), monomethylated (H3K4me1), dimethylated (H3K4me2) and trimethylated (H3K4me3) 'Lys-4' on histone H3. The order of binding preference is H3K4me3 > H3K4me2 > H3K4me1 > H3K4me0.
Target Subcellular Location
Nucleus, nucleoplasm. Nucleus matrix. Nucleus, PML body.
Target Tissue Specificity
Expressed in heart, placenta, skeletal muscle, brain, pancreas, lung, liver, but not kidney.
Target Research Area
Others
Target Synonyms
KIAA0136; Microrchidia 3; MORC family CW type zinc finger 3; MORC family CW type zinc finger protein 3; MORC family CW-type zinc finger protein 3; MORC3; MORC3_HUMAN; Nuclear matrix protein 2; Nuclear matrix protein NXP2; NXP2; ZCW5; ZCWCC3; Zinc finger CW type coiled coil domain 3; Zinc finger CW type coiled coil domain protein 3; Zinc finger CW type with coiled coil domain 3; Zinc finger CW-type coiled-coil domain protein 3
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