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Recombinant Human Myosin regulatory light chain 12A(MYL12A)

ACP00110

Number
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Specifications


Cat.No ACP00110 Target NameMYL12A
Target SynonymsEpididymis secretory protein Li 24;HEL-S-24;MLC-2B;Myosin RLC;Myosin regulatory light chain 2, nonsarcomeric;Myosin regulatory light chain MRLC3FormLiquid or Lyophilized powder
Expression SystemYeastExpression Range1-171aa
Mol Weight21.8 kDaProtein LengthFull length
PurityGreater than 95% as determined by SDS-PAGE.Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP19105
Background Information
  • Uniprot Id

    P19105

  • Target Species

    Human

  • Target Name

    MYL12A

  • Target Full Name

    Myosin regulatory light chain 12A

  • Target Research Area

    Signal Transduction

  • Target Synonyms

    ML12A_HUMAN; MLC 2B; MLC-2B; MLCB; MRCL3; MYL12A; Myosin regulatory light chain 12A; Myosin regulatory light chain 2; Myosin regulatory light chain 2, nonsarcomeric; Myosin regulatory light chain MRCL3; Myosin regulatory light chain MRLC3; Myosin RLC; Myosin, light polypeptide, regulatory, non sarcomeric (20kD); nonsarcomeric; RLC

  • Target Background

    This gene encodes a nonsarcomeric myosin regulatory light chain. This protein is activated by phosphorylation and regulates smooth muscle and non-muscle cell contraction. This protein may also be involved in DNA damage repair by sequestering the transcriptional regulator apoptosis-antagonizing transcription factor (AATF)/Che-1 which functions as a repressor of p53-driven apoptosis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8.

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