Recombinant Human N-acetylgalactosamine-6-sulfatase (GALNS)

ACP08988

Number

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Specifications

Cat.No	ACP08988	Target Name	GALNS
Target Synonyms	GALNSN-acetylgalactosamine-6-sulfatase; EC 3.1.6.4; Chondroitinsulfatase; Chondroitinase; Galactose-6-sulfate sulfatase; GalN6S; N-acetylgalactosamine-6-sulfate sulfatase; GalNAc6S sulfatase	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	27-522aa
Mol Weight	57.4kD	Protein Length	Full Length of Mature Protein
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	P34059

Background Information

Uniprot Id

P34059
Target Species

Human
Target Name

GALNS
Target Full Name

N-acetylgalactosamine-6-sulfatase
Target Involvement

Mucopolysaccharidosis 4A (MPS4A)
Target Subcellular Location

Lysosome.
Target Protein Families

Sulfatase family
Target Research Area

Signal Transduction
Target Synonyms

GALNSN-acetylgalactosamine-6-sulfatase; EC 3.1.6.4; Chondroitinsulfatase; Chondroitinase; Galactose-6-sulfate sulfatase; GalN6S; N-acetylgalactosamine-6-sulfate sulfatase; GalNAc6S sulfatase
Target Background

This gene encodes N-acetylgalactosamine-6-sulfatase which is a lysosomal exohydrolase required for the degradation of the glycosaminoglycans, keratan sulfate, and chondroitin 6-sulfate. Sequence alterations including point, missense and nonsense mutations, as well as those that affect splicing, result in a deficiency of this enzyme. Deficiencies of this enzyme lead to Morquio A syndrome, a lysosomal storage disorder.

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Recombinant Human N-acetylgalactosamine-6-sulfatase (GALNS)

Specifications

Immunogen Information

Inquire Recombinant Human N-acetylgalactosamine-6-sulfatase (GALNS) Now

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