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Recombinant Human N-cym protein (MYCNOS)

ACP23311

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP23311 Target NameMYCNOS
Target SynonymsMYCNOS; CYMN; NCYM; N-cym protein; N-myc opposite strandFormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-109
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP40205
Background Information
  • Uniprot Id

    P40205

  • Target Species

    Human

  • Target Name

    MYCNOS

  • Target Full Name

    N-cym protein

  • Target Function

    Regulates stability of MYCN in neuroblastoma cells by inhibiting GSK3B-mediated MYCN phosphorylation. Inhibits GSK3B activity by promoting its phosphorylation at 'Ser-9'.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Tissue Specificity

    Expressed in the neuronal cells of the cerebrum and cerebellum, spermatocytes of the testis, pancreatic cells and also the heart. Expressed in both primary and metastatic neuroblastomas and in thyroid tumors (at protein level). Expression is associated wi

  • Target Synonyms

    MYCNOS; CYMN; NCYM; N-cym protein; N-myc opposite strand

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