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| Cat.No | ACP04909 | Target Name | MT-ND4 |
|---|---|---|---|
| Target Synonyms | MT-ND4; MTND4; NADH dehydrogenase subunit 4; NADH-ubiquinone oxidoreductase chain 4; NADH4; ND4; NU4M_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P03905 |
|---|
Uniprot Id
P03905
Target Species
Human
Target Name
MT-ND4
Target Full Name
NADH-ubiquinone oxidoreductase chain 4
Target Function
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor. Essential for the catalytic activity and assembly of complex I.
Target Involvement
Leber hereditary optic neuropathy (LHON); Leber hereditary optic neuropathy with dystonia (LDYT); Mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS)
Target Subcellular Location
Mitochondrion inner membrane; Multi-pass membrane protein.
Target Protein Families
Complex I subunit 4 family
Target Synonyms
MT-ND4; MTND4; NADH dehydrogenase subunit 4; NADH-ubiquinone oxidoreductase chain 4; NADH4; ND4; NU4M_HUMAN
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