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| Cat.No | ACP20925 | Target Name | NRDC |
|---|---|---|---|
| Target Synonyms | NRDC; NRD1; Nardilysin; EC 3.4.24.61; N-arginine dibasic convertase; NRD convertase; NRD-C; Nardilysin convertase | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | O43847 |
|---|
Uniprot Id
O43847
Target Species
Human
Target Name
NRDC
Target Full Name
Nardilysin
Target Function
Cleaves peptide substrates on the N-terminus of arginine residues in dibasic pairs.
Target Protein Families
Peptidase M16 family
Target Tissue Specificity
Primarily in adult heart, skeletal muscle, and testis and at much lower levels in other tissues.
Target Synonyms
NRDC; NRD1; Nardilysin; EC 3.4.24.61; N-arginine dibasic convertase; NRD convertase; NRD-C; Nardilysin convertase
Target Background
This gene encodes a zinc-dependent endopeptidase that cleaves peptide substrates at the N-terminus of arginine residues in dibasic moieties and is a member of the peptidase M16 family. This protein interacts with heparin-binding EGF-like growth factor and plays a role in cell migration and proliferation. Multiple transcript variants encoding different isoforms have been found for this gene.
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