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| Cat.No | ACP16185 | Target Name | NBEAL2 |
|---|---|---|---|
| Target Synonyms | BDPLT4; GPS; NBEAL2; NBEL2_HUMAN; Neurobeachin-like protein 2; UNQ253/PRO290 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6ZNJ1 |
|---|
Uniprot Id
Q6ZNJ1
Target Species
Human
Target Name
NBEAL2
Target Full Name
Neurobeachin-like protein 2
Target Function
Probably involved in thrombopoiesis. Plays a role in the development or secretion of alpha-granules, that contain several growth factors important for platelet biogenesis.
Target Involvement
Gray platelet syndrome (GPS)
Target Subcellular Location
Endoplasmic reticulum.
Target Protein Families
WD repeat neurobeachin family
Target Tissue Specificity
Expressed in megakaryocytes.
Target Synonyms
BDPLT4; GPS; NBEAL2; NBEL2_HUMAN; Neurobeachin-like protein 2; UNQ253/PRO290
Target Background
The protein encoded by this gene contains a beige and Chediak-Higashi (BEACH) domain and multiple WD40 domains, and may play a role in megakaryocyte alpha-granule biogenesis. Mutations in this gene are a cause of gray platelet syndrome.
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