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| Cat.No | ACP22327 | Target Name | NMB |
|---|---|---|---|
| Target Synonyms | NMB; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B] | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 25-56 |
| Protein Length | Cytoplasmic Domain | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P08949 |
|---|
Uniprot Id
P08949
Target Species
Human
Target Name
NMB
Target Full Name
Neuromedin-B
Target Function
Stimulates smooth muscle contraction in a manner similar to that of bombesin.
Target Subcellular Location
Secreted.
Target Protein Families
Bombesin/neuromedin-B/ranatensin family
Target Synonyms
NMB; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]
Target Background
This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.
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