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Recombinant Human Neuromedin-B (NMB)

ACP22327

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP22327 Target NameNMB
Target SynonymsNMB; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range25-56
Protein LengthCytoplasmic DomainPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDP08949
Background Information
  • Uniprot Id

    P08949

  • Target Species

    Human

  • Target Name

    NMB

  • Target Full Name

    Neuromedin-B

  • Target Function

    Stimulates smooth muscle contraction in a manner similar to that of bombesin.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    Bombesin/neuromedin-B/ranatensin family

  • Target Synonyms

    NMB; Neuromedin-B [Cleaved into: Neuromedin-B-32; Neuromedin-B]

  • Target Background

    This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants.

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