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| Cat.No | ACP00532 | Target Name | NAV2 |
|---|---|---|---|
| Target Synonyms | Helicase APC down-regulated 1;Pore membrane and/or filament-interacting-like protein 2;Retinoic acid inducible in neuroblastoma 1;Steerin-2;Unc-53 homolog 2;unc53H2 | Form | Liquid or Lyophilized powder |
| Expression System | E.coli | Expression Range | 950-1100aa |
| Mol Weight | 22.9 kDa | Protein Length | Partial |
| Purity | Greater than 85% as determined by SDS-PAGE. | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8IVL1 |
|---|
Uniprot Id
Q8IVL1
Target Species
Human
Target Name
NAV2
Target Full Name
Neuron navigator 2
Target Function
Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.
Target Subcellular Location
Nucleus.
Target Protein Families
Nav/unc-53 family
Target Tissue Specificity
Highly expressed in the brain, kidney and liver. Also expressed in the thyroid, mammary gland, spinal cord, heart, placenta and lung. Abundantly expressed in colon cancers.
Target Research Area
Cancer
Target Synonyms
NAV2; HELAD1; KIAA1419; POMFIL2; RAINB1; STEERIN2Neuron navigator 2; EC 3.6.4.12; Helicase APC down-regulated 1; Pore membrane and/or filament-interacting-like protein 2; Retinoic acid inducible in neuroblastoma 1; Steerin-2; Unc-53 homolog 2; unc53H2
Target Background
This gene encodes a member of the neuron navigator gene family, which may play a role in cellular growth and migration. Multiple transcript variants encoding different isoforms have been found for this gene.
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