Recombinant Human Nitric oxide synthase, inducible (NOS2), Truncated

Cat.No	ACP23334	Target Name	NOS2
Target Synonyms	Hepatocyte; Peptidyl-cysteine S-nitrosylase NOS2, hepatocytes); Nitric oxide synthase; Nitric oxide synthase inducible ; nitric oxide synthase, Inducible, macrophage; NOS 2; NOS; Nos II; NOS type II; nos2; NOS2_HUMAN; NOS2A; NOS2A	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP23334

Target Name

NOS2

Target Synonyms

Hepatocyte; Peptidyl-cysteine S-nitrosylase NOS2, hepatocytes); Nitric oxide synthase; Nitric oxide synthase inducible ; nitric oxide synthase, Inducible, macrophage; NOS 2; NOS; Nos II; NOS type II; nos2; NOS2_HUMAN; NOS2A; NOS2A

Form

Lyophilized powder

Expression System

Custom Production. Please inquire and provide the desire expression system.

Protein Length

Partial

Purity

>85% (SDS-PAGE)

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	P35228

Background Information

Uniprot Id

P35228
Target Species

Human
Target Name

NOS2
Target Full Name

Nitric oxide synthase, inducible
Target Function

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such PTGS2/COX2. As component of the iNOS-S100A8/9 transnitrosylase complex involved in the selective inflammatory stimulus-dependent S-nitrosylation of GAPDH on 'Cys-247' implicated in regulation of the GAIT complex activity and probably multiple targets including ANXA5, EZR, MSN and VIM. Involved in inflammation, enhances the synthesis of proinflammatory mediators such as IL6 and IL8.
Target Subcellular Location

Cytoplasm, cytosol.
Target Protein Families

NOS family
Target Tissue Specificity

Expressed in the liver, retina, bone cells and airway epithelial cells of the lung. Not expressed in the platelets.
Target Research Area

Cancer
Target Synonyms

HEP-NOS; Hepatocyte NOS; HEPNOS ; inducible; Inducible nitric oxide synthase ; Inducible NO synthase; Inducible NOS; iNOS; MAC NOS; Macrophage NOS; Nitric oxide synthase 2 inducible; Nitric oxide synthase 2 inducible macrophage ; nitric oxide synthase 2A (inducible, hepatocytes); Nitric oxide synthase; Nitric oxide synthase inducible ; nitric oxide synthase, macrophage; NOS 2; NOS; Nos II; NOS type II; nos2; NOS2_HUMAN; NOS2A; NOS2A, Inducible, Hepatocyte; Peptidyl-cysteine S-nitrosylase NOS2
Target Background

Nitric oxide is a reactive free radical which acts as a biologic mediator in several processes, including neurotransmission and antimicrobial and antitumoral activities. This gene encodes a nitric oxide synthase which is expressed in liver and is inducible by a combination of lipopolysaccharide and certain cytokines. Three related pseudogenes are located within the Smith-Magenis syndrome region on chromosome 17.

Recombinant Human Nitric oxide synthase, inducible (NOS2), Truncated

Specifications

Immunogen Information

Inquire Recombinant Human Nitric oxide synthase, inducible (NOS2), Truncated Now

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