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Recombinant Human Nucleolar protein 58 (NOP58)

ACP09713

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP09713 Target NameNOP58
Target SynonymsHSPC120; NOL5; NOP5; NOP5/NOP58; NOP58; NOP58 ribonucleoprotein homolog (yeast); NOP58 ribonucleoprotein homolog; NOP58_HUMAN; Nucleolar protein 5; Nucleolar protein 58; Nucleolar protein NOP5/NOP58FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-529
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ9Y2X3
Background Information
  • Uniprot Id

    Q9Y2X3

  • Target Species

    Human

  • Target Name

    NOP58

  • Target Full Name

    Nucleolar protein 58

  • Target Function

    Required for 60S ribosomal subunit biogenesis. Core component of box C/D small nucleolar ribonucleoprotein (snoRNP) particles. Required for the biogenesis of box C/D snoRNAs such as U3, U8 and U14 snoRNAs.

  • Target Subcellular Location

    Nucleus, nucleolus. Nucleus, nucleoplasm.

  • Target Protein Families

    NOP5/NOP56 family

  • Target Tissue Specificity

    Ubiquitous.

  • Target Research Area

    Metabolism

  • Target Synonyms

    HSPC120; NOL5; NOP5; NOP5/NOP58; NOP58; NOP58 ribonucleoprotein homolog (yeast); NOP58 ribonucleoprotein homolog; NOP58_HUMAN; Nucleolar protein 5; Nucleolar protein 58; Nucleolar protein NOP5/NOP58

  • Target Background

    The protein encoded by this gene is a core component of box C/D small nucleolar ribonucleoproteins. Some box C/D small nucleolar RNAs (snoRNAs), such as U3, U8, and U14, are dependent upon the encoded protein for their synthesis. This protein is SUMOylated, which is necessary for high affinity binding to snoRNAs.

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