Home Products Recombinant Human Ornithine decarboxylase antizyme 3 (OAZ3)

Recombinant Human Ornithine decarboxylase antizyme 3 (OAZ3)

ACP18863

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Specifications

Cat.No	ACP18863	Target Name	OAZ3
Target Synonyms	Antizyme 3; AZ3; OAZ t; OAZ3; OAZ3_HUMAN; ODC-Az 3; Ornithine decarboxylase antizyme 3; RP11-98D18.13-004; Testicular secretory protein Li 31; TISP15	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-187
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q9UMX2

Background Information

Uniprot Id

Q9UMX2
Target Species

Human
Target Name

OAZ3
Target Full Name

Ornithine decarboxylase antizyme 3
Target Function

Ornithine decarboxylase (ODC) antizyme protein that negatively regulates ODC activity and intracellular polyamine biosynthesis and uptake in response to increased intracellular polyamine levels. Binds to ODC monomers, inhibiting the assembly of the functional ODC homodimers. Does not target the ODC monomers for degradation, which allows a protein synthesis-independent restoration of ODC activity. Stabilizes AZIN2 by interfering with its ubiquitination. Involved in the translocation of AZNI2 from ER-Golgi intermediate compartment (ERGIC) to the cytosol. Probably plays a key role in spermatogenesis by regulating the intracellular concentration of polyamines in haploid germ cells.
Target Subcellular Location

Nucleus. Cytoplasm.
Target Protein Families

ODC antizyme family
Target Tissue Specificity

Testis specific.
Target Synonyms

Antizyme 3; AZ3; OAZ t; OAZ3; OAZ3_HUMAN; ODC-Az 3; Ornithine decarboxylase antizyme 3; RP11-98D18.13-004; Testicular secretory protein Li 31; TISP15

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Recombinant Human Ornithine decarboxylase antizyme 3 (OAZ3)

Specifications

Immunogen Information

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