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| Cat.No | ACP07465 | Target Name | PANX1 |
|---|---|---|---|
| Target Synonyms | PANX1; MRS1; UNQ2529/PRO6028; Pannexin-1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q96RD7 |
|---|
Uniprot Id
Q96RD7
Target Species
Human
Target Name
PANX1
Target Full Name
Pannexin-1
Target Function
Structural component of the gap junctions and the hemichannels involved in the ATP release and nucleotide permeation. May play a role as a Ca(2+)-leak channel to regulate ER Ca(2+) homeostasis. Plays a critical role in oogenesis.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
Pannexin family
Target Tissue Specificity
Widely expressed. Highest expression is observed in oocytes and brain. Detected at very low levels in sperm cells.
Target Synonyms
PANX1; MRS1; UNQ2529/PRO6028; Pannexin-1
Target Background
The protein encoded by this gene belongs to the innexin family. Innexin family members are the structural components of gap junctions. This protein and pannexin 2 are abundantly expressed in central nerve system (CNS) and are coexpressed in various neuronal populations. Studies in Xenopus oocytes suggest that this protein alone and in combination with pannexin 2 may form cell type-specific gap junctions with distinct properties.
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