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| Cat.No | ACP19043 | Target Name | PANK4 |
|---|---|---|---|
| Target Synonyms | PANK4; 4'-phosphopantetheine phosphatase; EC 3.1.3.-; Inactive pantothenic acid kinase 4; hPanK4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NVE7 |
|---|
Uniprot Id
Q9NVE7
Target Species
Human
Target Name
PANK4
Target Full Name
4'-phosphopantetheine phosphatase
Target Function
May play a role in the physiological regulation of coenzyme A (CoA) intracellular levels (Probable). The phosphatase activity shows preference for normal or oxidatively damaged intermediates of 4'-phosphopantetheine, which provides strong indirect evidence that the phosphatase activity pre-empts damage in the CoA pathway. Hydrolyzing excess 4'-phosphopantetheine could constitute a directed overflow mechanism to prevent its oxidation to the S-sulfonate, sulfonate, or other forms. Hydrolyzing 4'-phosphopantetheine sulfonate or S-sulfonate would forestall their conversion to inactive forms of CoA and acyl carrier protein
Target Subcellular Location
Cytoplasm.
Target Protein Families
Type II pantothenate kinase family
Target Tissue Specificity
Ubiquitously expressed with higher expression in the muscle.
Target Synonyms
PANK4; 4'-phosphopantetheine phosphatase; EC 3.1.3.-; Inactive pantothenic acid kinase 4; hPanK4
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