Recombinant Human Paralemmin-1 (PALM)

The recombinant Human PALM was expressed with the amino acid range of 1-384. This PALM protein is expected to have a theoretical molecular weight of 45.7 kDa. Expression of this PALM protein is conducted in e.coli. The PALM coding gene included the N-terminal 6xHis tag, which simplifies the detection and purification processes of the recombinant PALM protein in following stages of expression and purification.Paralemmin-1 (PALM) is a membrane-associated phosphoprotein that is primarily expressed in the nervous system, particularly in neurons. It belongs to the paralemmin protein family and is associated with the cell membrane, where it plays a role in membrane dynamics and neuronal functions. PALM has been implicated in processes related to neurite outgrowth, axon guidance, and synaptic plasticity. Additionally, it may be involved in the regulation of ion channels and receptor trafficking within neurons. Research on PALM often focuses on understanding its precise functions in neural development, synaptic transmission, and the overall maintenance of neuronal structure and connectivity. Insights into PALM's roles may contribute to a better understanding of neurological disorders and potential therapeutic strategies.