Recombinant Human Peptidoglycan recognition protein 1 (PGLYRP1)

Discover the power of our Recombinant Human PGLYRP1, a valuable research tool for scientists studying Peptidoglycan recognition protein 1. This protein, also known as PGLYRP, PGRP, and TNFSF3L, plays an essential role in various cellular processes, making it a critical component in the field of Cancer research. Our Recombinant Human PGLYRP1 is a full-length mature protein (22-196aa) expressed in E. coli, ensuring a consistent and reliable source for your research endeavors. The protein is N-terminal 10xHis-tagged and C-terminal Myc-tagged, facilitating purification and detection processes. With a purity greater than 85% as determined by SDS-PAGE, and available in both liquid and lyophilized powder forms, this high-quality recombinant protein offers the precision and performance necessary for your Cancer studies.

ACP05210

Discover the power of our Recombinant Human PGLYRP1, a valuable research tool for scientists studying Peptidoglycan recognition protein 1. This protein, also known as PGLYRP, PGRP, and TNFSF3L, plays an essential role in various cellular processes, making it a critical component in the field of Cancer research.
Our Recombinant Human PGLYRP1 is a full-length mature protein (22-196aa) expressed in E. coli, ensuring a consistent and reliable source for your research endeavors. The protein is N-terminal 10xHis-tagged and C-terminal Myc-tagged, facilitating purification and detection processes. With a purity greater than 85% as determined by SDS-PAGE, and available in both liquid and lyophilized powder forms, this high-quality recombinant protein offers the precision and performance necessary for your Cancer studies.

Number

Cat.No	ACP05210	Target Name	PGLYRP1
Target Synonyms	member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF 3L; TNFSF3L; UNQ639/PRO1269, MGC126894; MGC126896; Peptidoglycan recognition protein 1; Peptidoglycan recognition protein; Peptidoglycan recognition protein short; PGLYRP; PGLYRP1; PGRP; PGRP S; PGRP-S; PGRP1_HUMAN; PHRP, short; SBBI68; TAG7; TNF superfamily	Form	Liquid or Lyophilized powder
Expression System	E.coli	Expression Range	22-196aa
Mol Weight	26.9 kDa	Protein Length	Full Length of Mature Protein
Purity	Greater than 85% as determined by SDS-PAGE.	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Cat.No

ACP05210

Target Name

PGLYRP1

Target Synonyms

member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF 3L; TNFSF3L; UNQ639/PRO1269, MGC126894; MGC126896; Peptidoglycan recognition protein 1; Peptidoglycan recognition protein; Peptidoglycan recognition protein short; PGLYRP; PGLYRP1; PGRP; PGRP S; PGRP-S; PGRP1_HUMAN; PHRP, short; SBBI68; TAG7; TNF superfamily

Form

Liquid or Lyophilized powder

Expression System

E.coli

Expression Range

22-196aa

Mol Weight

26.9 kDa

Protein Length

Full Length of Mature Protein

Purity

Greater than 85% as determined by SDS-PAGE.

Storage Buffer

5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Target Species	Human	Uniprot ID	O75594

Background Information

Uniprot Id

O75594
Target Species

Human
Target Name

PGLYRP1
Target Full Name

Peptidoglycan recognition protein 1
Target Function

Innate immunity protein that plays several important functions in antimicrobial and antitumor defense systems. Acts as a pattern receptor that binds to murein peptidoglycans (PGN) of Gram-positive bacteria and thus provides bactericidal activity. Forms an equimolar complex with heat shock protein HSPA1A and induces programmed cell death through apoptosis and necroptosis in tumor cell lines by activating the TNFR1 receptor on the target cell membrane. In addition, acts in complex with the Ca(2+)-binding protein S100A4 as a chemoattractant able to induce lymphocyte movement. Mechanistically, this complex acts as a ligand of the chemotactic receptors CCR5 and CXCR3 which are present on the cells of the immune system. Promotes also the activation of lymphocytes that become able to kill virus-infected cells as well as tumor cells by modulating the spectrum of their target-cell specificity. Induction of cytotoxicity on monocyte surface requires interaction with TREM1 receptor.
Target Subcellular Location

Secreted. Cytoplasmic granule.
Target Protein Families

N-acetylmuramoyl-L-alanine amidase 2 family
Target Tissue Specificity

Highly expressed in bone marrow. Weak expression found in kidney, liver, small intestine, spleen, thymus, peripheral leukocyte, lung, fetal spleen and neutrophils.
Target Research Area

Cancer
Target Synonyms

MGC126894; MGC126896; Peptidoglycan recognition protein 1; Peptidoglycan recognition protein; Peptidoglycan recognition protein short; PGLYRP; PGLYRP1; PGRP; PGRP S; PGRP-S; PGRP1_HUMAN; PHRP, short; SBBI68; TAG7; TNF superfamily, member 3 (LTB)-like (peptidoglycan recognition protein); TNFSF 3L; TNFSF3L; UNQ639/PRO1269
Target Background

Enables peptidoglycan binding activity and peptidoglycan immune receptor activity. Involved in antimicrobial humoral immune response mediated by antimicrobial peptide; killing of cells of other organism; and response to bacterium. Located in extracellular exosome.

Recombinant Human Peptidoglycan recognition protein 1 (PGLYRP1)

Specifications

Immunogen Information

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