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| Cat.No | ACP22969 | Target Name | BRPF1 |
|---|---|---|---|
| Target Synonyms | BR140; Bromodomain and PHD finger containing 1; Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein; 140kD ; BRPF1; BRPF1_HUMAN; Peregrin; Protein Br140 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P55201 |
|---|
Uniprot Id
P55201
Target Species
Human
Target Name
BRPF1
Target Full Name
Peregrin
Target Function
Scaffold subunit of various histone acetyltransferase (HAT) complexes, such as the MOZ/MORF and HBO1 complexes, which have a histone H3 acetyltransferase activity. Plays a key role in HBO1 complex by directing KAT7/HBO1 specificity towards histone H3 'Lys-14' acetylation (H3K14ac). Some HAT complexes preferentially mediate histone H3 'Lys-23' (H3K23ac) acetylation. Positively regulates the transcription of RUNX1 and RUNX2.
Target Involvement
Intellectual developmental disorder with dysmorphic facies and ptosis (IDDDFP)
Target Subcellular Location
Nucleus. Chromosome. Cytoplasm.
Target Tissue Specificity
High levels in testis.
Target Synonyms
BR140; Bromodomain and PHD finger containing 1; Bromodomain and PHD finger-containing protein 1; bromodomain-containing protein; 140kD ; BRPF1; BRPF1_HUMAN; Peregrin; Protein Br140
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