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| Cat.No | ACP24456 | Target Name | NUDT7 |
|---|---|---|---|
| Target Synonyms | NUDT7; Peroxisomal coenzyme A diphosphatase NUDT7; EC 3.6.1.-; Nucleoside diphosphate-linked moiety X motif 7; Nudix motif 7 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-238 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P0C024 |
|---|
Uniprot Id
P0C024
Target Species
Human
Target Name
NUDT7
Target Full Name
Peroxisomal coenzyme A diphosphatase NUDT7
Target Function
Fatty acyl-coenzyme A (CoA) diphosphatase that hydrolyzes fatty acyl-CoA to yield acyl-4'-phosphopantetheine and adenosine 3',5'-bisphosphate. Cleaves CoA, CoA esters and oxidized CoA with similar efficiencies. Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs. Has no activity toward NDP-sugars, CDP-alcohols, (deoxy)nucleoside 5'-triphosphates, nucleoside 5'-di or monophosphates, diadenosine polyphosphates, NAD, NADH, NADP, NADPH or thymidine-5'-monophospho-p-nitrophenyl ester. May be required to eliminate oxidized CoA from peroxisomes, or regulate CoA and acyl-CoA levels in this organelle in response to metabolic demand. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. Exhibits decapping activity towards dpCoA-capped RNAs in vitro
Target Subcellular Location
Peroxisome.
Target Protein Families
Nudix hydrolase family, PCD1 subfamily
Target Tissue Specificity
Expressed in liver, kidney, pancreas, pituitary, small intestine, spleen, heart and placenta. Weakly expressed in brain.
Target Synonyms
NUDT7; Peroxisomal coenzyme A diphosphatase NUDT7; EC 3.6.1.-; Nucleoside diphosphate-linked moiety X motif 7; Nudix motif 7
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