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| Cat.No | ACP19138 | Target Name | PHF23 |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-403 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9BUL5 |
|---|
Uniprot Id
Q9BUL5
Target Species
Human
Target Name
PHF23
Target Full Name
PHD finger protein 23
Target Function
Acts as a negative regulator of autophagy, through promoting ubiquitination and degradation of LRSAM1, an E3 ubiquitin ligase that promotes autophagy in response to starvation or infecting bacteria.
Target Involvement
A chromosomal aberration involving PHF23 is found in a patient with acute myeloid leukemia (AML). Translocation t(11;17)(p15;p13) with NUP98.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
PHF23 family
Target Tissue Specificity
Widely expressed in human tissues and various cell lines.
Target Synonyms
410141M05Rik; FLJ16355; FLJ22884; hJUNE 1b ; JUNE-1; MGC2941; P23-172M21.13-002; PDH containing protein JUNE 1; PDH-containing protein JUNE-1; PHD finger protein 23; PHD finger protein 23a ; PHF23; PHF23_HUMAN; RP23-172M21.13
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