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| Cat.No | ACP19045 | Target Name | PLSCR2 |
|---|---|---|---|
| Target Synonyms | PLSCR2; Phospholipid scramblase 2; PL scramblase 2; Ca(2+)-dependent phospholipid scramblase 2 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NRY7 |
|---|
Uniprot Id
Q9NRY7
Target Species
Human
Target Name
PLSCR2
Target Full Name
Phospholipid scramblase 2
Target Function
May mediate accelerated ATP-independent bidirectional transbilayer migration of phospholipids upon binding calcium ions that results in a loss of phospholipid asymmetry in the plasma membrane. May play a central role in the initiation of fibrin clot formation, in the activation of mast cells and in the recognition of apoptotic and injured cells by the reticuloendothelial system.; Isoform 1 has no prospholipid scramblase activity, due to the lack of a N-terminal proline-rich domain.
Target Subcellular Location
Membrane; Single-pass type II membrane protein.; [Isoform 1]: Nucleus.
Target Protein Families
Phospholipid scramblase family
Target Tissue Specificity
Expression of isoform 1 seems restricted to testis.
Target Synonyms
PLSCR2; Phospholipid scramblase 2; PL scramblase 2; Ca(2+)-dependent phospholipid scramblase 2
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