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| Cat.No | ACP11702 | Target Name | PLEK2 |
|---|---|---|---|
| Target Synonyms | Pleckstrin 2 (mouse) homolog; Pleckstrin 2; Pleckstrin-2; PLEK 2; PLEK2; PLEK2_HUMAN | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 1-353 |
| Protein Length | Full length protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q9NYT0 |
|---|
Uniprot Id
Q9NYT0
Target Species
Human
Target Name
PLEK2
Target Full Name
Pleckstrin-2
Target Function
May help orchestrate cytoskeletal arrangement. Contribute to lamellipodia formation.
Target Subcellular Location
Cell projection, lamellipodium membrane; Peripheral membrane protein. Cytoplasm, cytoskeleton.
Target Synonyms
Pleckstrin 2 (mouse) homolog; Pleckstrin 2; Pleckstrin-2; PLEK 2; PLEK2; PLEK2_HUMAN
Target Background
The protein encoded by this gene associates with membrane-bound phosphatidylinositols generated by phosphatidylinositol 3-kinase. The encoded protein then interacts with the actin cytoskeleton to induce cell spreading. In conjunction with complement component 1, q subcomponent, B chain (C1QB), this gene shows an increase in expression in melanoma cells and may serve as an accurate biomarker for the disease.
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