Home Products Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1)

Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1)

ACP03257

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Specifications

Cat.No	ACP03257	Target Name	PLEKHF1
Form	Liquid or Lyophilized powder	Expression System	Baculovirus
Expression Range	1-279aa	Mol Weight	35.2 kDa
Protein Length	Full length	Purity	Greater than 85% as determined by SDS-PAGE.
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q96S99

Background Information

Uniprot Id

Q96S99
Target Species

Human
Target Name

PLEKHF1
Target Full Name

Pleckstrin homology domain-containing family F member 1
Target Function

May induce apoptosis through the lysosomal-mitochondrial pathway. Translocates to the lysosome initiating the permeabilization of lysosomal membrane (LMP) and resulting in the release of CTSD and CTSL to the cytoplasm. Triggers the caspase-independent apoptosis by altering mitochondrial membrane permeabilization (MMP) resulting in the release of PDCD8.
Target Subcellular Location

Nucleus. Cytoplasm, perinuclear region. Lysosome. Note=Translocates to lysosome during apoptosis.
Target Tissue Specificity

Highly expressed in heart and skeletal muscle. Weakly expressed in brain, thymus, spleen, kidney, liver, small intestine, placenta and lung.
Target Research Area

Others
Target Synonyms

PLEKHF1; APPD; LAPF; ZFYVE15; Pleckstrin homology domain-containing family F member 1; PH domain-containing family F member 1; Lysosome-associated apoptosis-inducing protein containing PH and FYVE domains; Apoptosis-inducing protein; PH and FYVE domain-containing protein 1; Phafin-1; Zinc finger FYVE domain-containing protein 15

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Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1)

Specifications

Immunogen Information

Inquire Recombinant Human Pleckstrin homology domain-containing family F member 1 (PLEKHF1) Now

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