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Recombinant Human Poly (A) RNA polymerase GLD2 (PAPD4)

ACP16344

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP16344 Target NamePAPD4
Target SynonymsTENT2; GLD2; PAPD4Poly(A) RNA polymerase GLD2; hGLD-2; EC 2.7.7.19; PAP-associated domain-containing protein 4; Terminal nucleotidyltransferase 2; Terminal uridylyltransferase 2; TUTase 2FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range1-484
Protein LengthFull length proteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDQ6PIY7
Background Information
  • Uniprot Id

    Q6PIY7

  • Target Species

    Human

  • Target Name

    TENT2

  • Target Full Name

    Poly(A) RNA polymerase GLD2

  • Target Function

    Cytoplasmic poly(A) RNA polymerase that adds successive AMP monomers to the 3'-end of specific RNAs, forming a poly(A) tail. In contrast to the canonical nuclear poly(A) RNA polymerase, it only adds poly(A) to selected cytoplasmic mRNAs. Does not play a role in replication-dependent histone mRNA degradation. Adds a single nucleotide to the 3' end of specific miRNAs, monoadenylation stabilizes and prolongs the activity of some but not all miRNAs.

  • Target Subcellular Location

    Cytoplasm. Nucleus.

  • Target Protein Families

    DNA polymerase type-B-like family, GLD2 subfamily

  • Target Tissue Specificity

    Expressed in brain. Within brain, it is expressed in cerebellum, hippocampus and medulla.

  • Target Synonyms

    TENT2; GLD2; PAPD4Poly(A) RNA polymerase GLD2; hGLD-2; EC 2.7.7.19; PAP-associated domain-containing protein 4; Terminal nucleotidyltransferase 2; Terminal uridylyltransferase 2; TUTase 2

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