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Recombinant Human Polycomb group RING finger protein 3 (PCGF3)

ACP17496

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Specifications

Cat.No	ACP17496	Target Name	PCGF3
Target Synonyms	DONG1; PCGF3; PCGF3_HUMAN; Polycomb group ring finger 3; Polycomb group RING finger protein 3; Ring finger protein 3; RING finger protein 3A; RNF3A	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Expression Range	1-242
Protein Length	Full length protein	Purity	>85% (SDS-PAGE)
Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q3KNV8

Background Information

Uniprot Id

Q3KNV8
Target Species

Human
Target Name

PCGF3
Target Full Name

Polycomb group RING finger protein 3
Target Function

Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. Within the PRC1-like complex, regulates RNF2 ubiquitin ligase activity. Plays a redundant role with PCGF5 as part of a PRC1-like complex that mediates monoubiquitination of histone H2A 'Lys-119' on the X chromosome and is required for normal silencing of one copy of the X chromosome in XX females
Target Subcellular Location

Nucleus. Nucleus, nucleoplasm.
Target Synonyms

DONG1; PCGF3; PCGF3_HUMAN; Polycomb group ring finger 3; Polycomb group RING finger protein 3; Ring finger protein 3; RING finger protein 3A; RNF3A

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Recombinant Human Polycomb group RING finger protein 3 (PCGF3)

Specifications

Immunogen Information

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