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The production of recombinant Human PSG1 protein involves manipulating the expression of the desired gene in e.coli cells. The sequence (35-419aa) of foreign DNA is merged with an expression vector and subsequently introduced into e.coli cells. Positive cells are chosen and cultivated to induce the expression of the desired protein. A N-terminal 6xHis tag is fused to the protein. The resulting recombinant Human PSG1 protein undergoes purification through affinity purification, with a purity exceeding 85%, as confirmed by SDS-PAGE.
The production of recombinant Human PSG1 protein involves manipulating the expression of the desired gene in e.coli cells. The sequence (35-419aa) of foreign DNA is merged with an expression vector and subsequently introduced into e.coli cells. Positive cells are chosen and cultivated to induce the expression of the desired protein. A N-terminal 6xHis tag is fused to the protein. The resulting recombinant Human PSG1 protein undergoes purification through affinity purification, with a purity exceeding 85%, as confirmed by SDS-PAGE.
| Cat.No | ACP01040 | Target Name | PSG1 |
|---|---|---|---|
| Form | Liquid or Lyophilized powder | Expression System | E.coli |
| Expression Range | 35-419aa | Mol Weight | 49.5 kDa |
| Protein Length | Full Length of Mature Protein | Purity | Greater than 85% as determined by SDS-PAGE. |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | P11464 |
|---|
Uniprot Id
P11464
Target Species
Human
Target Name
PSG1
Target Full Name
Pregnancy-specific beta-1-glycoprotein 1
Target Subcellular Location
Secreted.
Target Protein Families
Immunoglobulin superfamily, CEA family
Target Research Area
Tags & Cell Markers
Target Synonyms
B1G1; Carcinoembryonic antigen SG8; CD66 antigen-like family member F; CD66f; CD66f antigen; CEA; DHFRP2; Fetal liver non-specific cross-reactive antigen 1/2; FL-NCA-1/2; PBG 1; PBG1; Pregnancy specific B 1 glycoprotein; Pregnancy specific beta 1 glycoprotein 1; Pregnancy specific beta 1 glycoprotein 2; Pregnancy specific beta 1 glycoprotein 7; Pregnancy specific beta 1 glycoprotein 8; Pregnancy specific beta 1 glycoprotein; Pregnancy specific beta 1 glycoprotein C/D; Pregnancy-specific beta-1 glycoprotein C/D; Pregnancy-specific beta-1-glycoprotein 1; Pregnancy-specific glycoprotein 1; PS beta C/D; PS-beta-C/D; PS-beta-G-1; PSBG 1; PSBG 2; PSBG-1; PSBG1; PSBG2; PSG 1; PSG 2; PSG 8; PSG 95; PSG IIA d; PSG1; PSG1_HUMAN; PSG2; PSG8; PSG95; PSGGA; PSGGB; PSGIIA a; PSGIIA; PSGIIA b; PSGIIA c; SP 1; SP1
Target Background
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).
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