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| Cat.No | ACP15925 | Target Name | PM20D1 |
|---|---|---|---|
| Target Synonyms | PM20D1; N-fatty-acyl-amino acid synthase/hydrolase PM20D1; EC 3.5.1.-; EC 4.3.-.-; Peptidase M20 domain-containing protein 1 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Expression Range | 26-502 |
| Protein Length | Full Length of Mature Protein | Purity | >85% (SDS-PAGE) |
| Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q6GTS8 |
|---|
Uniprot Id
Q6GTS8
Target Species
Human
Target Name
PM20D1
Target Full Name
N-fatty-acyl-amino acid synthase/hydrolase PM20D1
Target Function
Secreted enzyme that regulates the endogenous N-fatty acyl amino acid (NAAs) tissue and circulating levels by functioning as a bidirectional NAA synthase/hydrolase. It condenses free fatty acids and free amino acids to generate NAAs and bidirectionally catalyzes the reverse hydrolysis reaction. Some of these NAAs stimulate oxidative metabolism via mitochondrial uncoupling, increasing energy expenditure in a UPC1-independent manner. Thereby, this secreted protein may indirectly regulate whole body energy expenditure. PM20D1 circulates in tight association with both low- and high-density (LDL and HDL,respectively) lipoprotein particles
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase M20A family
Target Synonyms
PM20D1; N-fatty-acyl-amino acid synthase/hydrolase PM20D1; EC 3.5.1.-; EC 4.3.-.-; Peptidase M20 domain-containing protein 1
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