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| Cat.No | ACP08513 | Target Name | PRRT1 |
|---|---|---|---|
| Target Synonyms | PRRT1; C6orf31; NG5; Proline-rich transmembrane protein 1; Dispanin subfamily D member 1; DSPD1; Synapse differentiation-induced protein 4; SynDIG4 | Form | Lyophilized powder |
| Expression System | Custom Production. Please inquire and provide the desire expression system. | Protein Length | Partial |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q99946 |
|---|
Uniprot Id
Q99946
Target Species
Human
Target Name
PRRT1
Target Full Name
Proline-rich transmembrane protein 1
Target Function
Required to maintain a pool of extrasynaptic AMPA-regulated glutamate receptors (AMPAR) which is necessary for synapse development and function. Regulates basal AMPAR function and synaptic transmission during development but is dispensable at mature hippocampal synapses. Plays a role in regulating basal phosphorylation levels of glutamate receptor GRIA1 and promotes GRIA1 and GRIA2 cell surface expression.
Target Subcellular Location
Cell membrane; Single-pass type II membrane protein. Cell junction, synapse.
Target Protein Families
CD225/Dispanin family
Target Synonyms
PRRT1; C6orf31; NG5; Proline-rich transmembrane protein 1; Dispanin subfamily D member 1; DSPD1; Synapse differentiation-induced protein 4; SynDIG4
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