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Recombinant Human Prostacyclin synthase (PTGIS), Truncated

ACP17703

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Specifications

Cat.No	ACP17703	Target Name	PTGIS
Target Synonyms	CYP8; CYP8A1; Cytochrome P450, family 8, polypeptide 1; EC 5.3.99.4; MGC126858; MGC126860; OTTHUMP00000031777; PGIS; Prostacyclin synthase; Prostaglandin I2 (prostacyclin) synthase; Prostaglandin I2 synthase; PTGI; PTGIS; PTGIS_HUMAN, subfamily A	Form	Lyophilized powder
Expression System	Custom Production. Please inquire and provide the desire expression system.	Protein Length	Partial
Purity	>85% (SDS-PAGE)	Storage Buffer	5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information

Target Species	Human	Uniprot ID	Q16647

Background Information

Uniprot Id

Q16647
Target Species

Human
Target Name

PTGIS
Target Full Name

Prostacyclin synthase
Target Function

Catalyzes the biosynthesis and metabolism of eicosanoids. Catalyzes the isomerization of prostaglandin H2 to prostacyclin (= prostaglandin I2), a potent mediator of vasodilation and inhibitor of platelet aggregation. Additionally, displays dehydratase activity, toward hydroperoxyeicosatetraenoates (HPETEs), especially toward (15S)-hydroperoxy-(5Z,8Z,11Z,13E)-eicosatetraenoate (15(S)-HPETE).
Target Involvement

Essential hypertension (EHT)
Target Subcellular Location

Endoplasmic reticulum membrane; Single-pass membrane protein.
Target Protein Families

Cytochrome P450 family
Target Tissue Specificity

Widely expressed; particularly abundant in ovary, heart, skeletal muscle, lung and prostate.
Target Synonyms

CYP8; CYP8A1; Cytochrome P450, family 8, subfamily A, polypeptide 1; EC 5.3.99.4; MGC126858; MGC126860; OTTHUMP00000031777; PGIS; Prostacyclin synthase; Prostaglandin I2 (prostacyclin) synthase; Prostaglandin I2 synthase; PTGI; PTGIS; PTGIS_HUMAN

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Recombinant Human Prostacyclin synthase (PTGIS), Truncated

Specifications

Immunogen Information

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