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Recombinant Human Protein CREG1 (CREG1)

ACP21243

Number
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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ACP21243 Target NameCREG1
Target SynonymsCellular repressor of E1A stimulated genes 1; Cellular repressor of E1A-stimulated genes 1; CREG; CREG1; CREG1_HUMAN; Protein CREG1FormLyophilized powder
Expression SystemCustom Production. Please inquire and provide the desire expression system.Expression Range32-220
Protein LengthFull Length of Mature ProteinPurity>85% (SDS-PAGE)
Storage Buffer5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0.

Immunogen Information


Target SpeciesHumanUniprot IDO75629
Background Information
  • Uniprot Id

    O75629

  • Target Species

    Human

  • Target Name

    CREG1

  • Target Full Name

    Protein CREG1

  • Target Function

    May contribute to the transcriptional control of cell growth and differentiation. Antagonizes transcriptional activation and cellular transformation by the adenovirus E1A protein. The transcriptional control activity of cell growth requires interaction with IGF2R.

  • Target Subcellular Location

    Secreted.

  • Target Protein Families

    CREG family

  • Target Synonyms

    Cellular repressor of E1A stimulated genes 1; Cellular repressor of E1A-stimulated genes 1; CREG; CREG1; CREG1_HUMAN; Protein CREG1

  • Target Background

    The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation.

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