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| Cat.No | ACP14538 | Target Name | DBF4B |
|---|---|---|---|
| Form | Lyophilized powder | Expression System | Custom Production. Please inquire and provide the desire expression system. |
| Expression Range | 1-615 | Protein Length | Full length protein |
| Purity | >85% (SDS-PAGE) | Storage Buffer | 5%-50% glycerol. Lyophilized powder form: the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, Liquid form: default storage buffer is Tris/PBS-based buffer, pH 8.0. |
| Target Species | Human | Uniprot ID | Q8NFT6 |
|---|
Uniprot Id
Q8NFT6
Target Species
Human
Target Name
DBF4B
Target Full Name
Protein DBF4 homolog B
Target Function
Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S and M phases. The complex CDC7-DBF4B selectively phosphorylates MCM2 subunit at 'Ser-40' and then is involved in regulating the initiation of DNA replication during cell cycle.
Target Subcellular Location
Nucleus. Note=Predominantly found in soluble fraction but not in the chromatin-bound fraction.
Target Tissue Specificity
Widely expressed. Highly expressed in testis.
Target Synonyms
Activator of S phase kinase like protein 1 ; Activator of S phase kinase-like protein 1; ASK like protein 1; ASK-like protein 1; ASKL1 ; chifb ; Chiffon homolog B; DBF 4B; DBF4 homolog B (S. cerevisiae) ; DBF4 homolog B; Dbf4 related factor 1; Dbf4-related factor 1; dbf4b; DBF4B_HUMAN; DRF1 ; FLJ13087; MGC15009; Protein DBF4 homolog B; ZDBF1B ; Zinc finger DBF type containing 1B
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